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Pfizer Animal Health Introduces Zylexis(TM)

New York, NY (February 8, 2006) -- Pfizer Animal Health recently introduced its newest product offering for equine veterinarians. Zylexis(TM) is a demonstrated safe and effective immunomodulator backed by contact challenge study data and nearly a decade of patient use by practitioners in Germany.

Zylexis is thought to work by preparing the horse’s immune system, in advance, to function more efficiently against equine herpesvirus (EHV) types 1 and 4 pathogens and is offered specifically as an aid in reducing upper respiratory disease caused by these viruses. Zylexis is created with an inactive (killed) preparation of Parapox Ovis Virus.

While an immunomodulator, like Zylexis, can’t prevent a horse from contracting a disease such as EHV, it can help to reduce the severity of upper respiratory symptoms the horse will suffer after it is exposed. And by keeping symptoms under control, owners may lose much less of their valuable training and competition time.

“Zylexis has been used for eight years in Germany,” said Dr. Robert Holland, Senior Veterinarian at Pfizer Animal Health. “It won’t stop EHV-1 or -4, but our study shows that it can limit the severity and duration of symptoms. This product provides practitioners with a valuable tool to help horses deal with the EHV types 1 and 4 pathogens they may encounter in show and stable environments.”

Equine herpesvirus is a disease of serious concern to horse owners -- particularly those whose horses travel to meet show, race and competition schedules. Outbreaks of the virus have made front-page news in recent years, forcing numerous racetracks and well-known stables -- such as Churchill Downs, Turfway Park, and the University of Findlay in Ohio -- to put animals in quarantine to protect the rest of the equine population.

“Equine herpesvirus is extremely contagious, and a large portion of horses in the U.S. today are already latent carriers of the disease,” said Dr. Holland. “When they are stressed by factors such as performance, travel or competition, these carrier horses may suddenly come down with active disease and show symptoms. EHV can then spread rapidly through a barn, endangering all of the horses in the area.”

For more information on Pfizer Animal Health’s complete line of equine health care products, visit http://www.pfizer.com/equine. Pfizer Inc discovers, develops, manufactures and markets leading prescription medicines, for humans and animals, and many of the world’s best known consumer products.


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